Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection

What is Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection?

Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection is a rare primary immunodeficiency due to a defect in innate immunity disorder characterized by selective susceptibility to viral infections, particularly after systemic challenge with live viral vaccines, such as the measles, mumps and rubella (MMR) vaccine. Patients present severe, potentially fatal, manifestations to viral illness, including encephalitis, hepatitis and pneumonitis.

Other condition names

  • Primary immunodeficiency with post-MMR vaccine viral infection

Inheritance type

Autosomal recessive

Prevalence

  • Worldwide: <1 in 1,000 000

Age of Onset

  • Infancy
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