ALECT2 amyloidosis

What is ALECT2 amyloidosis?

A rare, systemic amyloidosis characterized by slowly progressive renal disease presenting with proteinuria, hypertension and decreased glomerular filtration rate leading to progressive renal failure. Histology reveals amyloid deposits of leukocyte chemotactic factor-2 protein in the renal cortical interstitium, tubular basement membranes, glomeruli and the vessel walls. Extra-renal deposits can be seen in the liver, lungs, spleen and adrenal glands.

Other condition names

  • Leukocyte chemotactic factor-2 amyloidosis

Inheritance type

Not applicable

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