Anti-glomerular basement membrane disease

What is Anti-glomerular basement membrane disease?

A rapidly progressive and generally fulminant rare autoimmune condition characterized by the presence of anti-GBM antibodies, affecting glomerular and/or pulmonary capillaries. It may manifest as an isolated glomerulonephritis (anti-GBM nephritis) or as a pulmonary-renal syndrome with severe lung hemorrhage (Goodpasture's syndrome).

Other condition names

  • Anti-GBM syndrome
  • Goodpasture syndrome

Inheritance type

Not applicable


  • Europe: 1-9 in 1,000 000

Age of Onset

  • Adolescent
  • Adult
  • Elderly
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