Anti-glomerular basement membrane disease

What is Anti-glomerular basement membrane disease?

A rare, fulminant small vessel vasculitis that affects the capillary beds of the kidneys and lungs and characterized by the presence of anti-glomerular basement membrane (GBM) and, in its full-blown form, anti-alveolar basement membrane (ABM) antibodies. Consequently, it may manifest as a rapidly progressive, isolated glomerulonephritis (anti-GBM nephritis) or as a pulmonary-renal syndrome with severe lung hemorrhage.

Other condition names

  • Anti-GBM syndrome
  • Goodpasture syndrome

Inheritance type

Not applicable

Prevalence

  • Europe: 1-9 in 1,000 000

Age of Onset

  • Adolescent
  • Adult
  • Elderly
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.