Benign recurrent intrahepatic cholestasis

What is Benign recurrent intrahepatic cholestasis?

Benign recurrent intrahepatic cholestasis (BRIC) is a hereditary liver disorder characterized by intermittent episodes of intrahepatic cholestasis, generally without progression to chronic liver damage. BRIC is now believed to belong to a clinical spectrum of intrahepatic cholestatic disorders that ranges from the mild intermittent attacks in BRIC to the severe, chronic and progressive cholestasis seen in progressive familial intrahepatic cholestasis (PFIC; see this term).

Other condition names

  • BRIC
  • Summerskill-Walshe-Tygstrup syndrome

Inheritance type

Autosomal dominant, Autosomal recessive

Age of Onset

  • All ages
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