Central diabetes insipidus

What is Central diabetes insipidus?

Central diabetes insipidus (CDI) is a hypothalamus-pituitary disease characterized by polyuria and polydipsia due to a vasopressin (AVP) deficiency. It can be inherited or acquired (hereditary CDI and acquired CDI; see these terms).

Other condition names

  • CDI
  • Neurogenic diabetes insipidus

Inheritance type

Autosomal dominant, Autosomal recessive, X-linked dominant


  • Europe: 1-9 in 100,000

Age of Onset

  • Childhood
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.