Congenital factor XII deficiency

What is Congenital factor XII deficiency?

A rare, autosomal recessive systemic dysfunction of the hemostatic pathway, that is due to a defect in the coagulation factor XII (FXII or Hageman factor), and is either asymptomatic or characterized by a prolonged activated partial thromboplastin time and an increased risk for thromboembolism. FXII deficiency is strongly associated with primary recurrent abortions.

Other condition names

  • Congenital Hageman factor deficiency

Inheritance type

Autosomal recessive

Age of Onset

  • All ages
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