Exercise-induced malignant hyperthermia

What is Exercise-induced malignant hyperthermia?

A rare disease with malignant hyperthermia characterized by exercise-induced life-threatening hyperthermia with a body temperature over 40°C and signs of encephalopathy ranging from confusion to convulsions or coma. Incidence increases with rising ambient temperature and relative humidity. Manifestations may include rhabdomyolysis (presenting with myalgia, muscle weakness, and myoglobinuria), tachycardia, and in severe cases multiorgan failure.

Other condition names

  • Exertional heat stroke

Inheritance type



  • Worldwide: Unknown

Age of Onset

  • All ages
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