Familial progressive hyperpigmentation

What is Familial progressive hyperpigmentation?

Familial progressive hyperpigmentation is a rare, genetic, skin pigmentation anomaly disorder characterized by irregular patches of hyperpigmented skin which present at birth or in early infancy and increase in size, number and confluence with age. Affected areas of the body include the face, neck, trunk and limbs, as well as the palms, soles, oral mucosa and conjuctiva. No hypogmentation macules are observed and no systemic diseases are associated.

Other condition names

  • Melanosis diffusa congenita
  • Melanosis universalis hereditaria
  • Universal melanosis

Inheritance type

Autosomal dominant

Age of Onset

  • Infancy
  • Neonatal
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