Febrile infection-related epilepsy syndrome
What is Febrile infection-related epilepsy syndrome?
A rare, potentially fatal , epileptic encephalopathy characterized by explosive-onset of recurrent multifocal and bilateral tonic-clonic seizures following an unspecific febrile illness. The syndrome develops without a clear acute structural, toxic or metabolic cause, in a patient without previous epilepsy. FIRES is a subgroup of new-onset refractory status epilepticus (NORSE), and requires a preceding febrile infection as a mandatory feature.
Other condition names
- AERRPS
- Acute encephalitis with refractory repetitive partial seizures
- Acute non-herpetic encephalitis with severe refractory status epilepticus
- DESC syndrome
- Devastating epileptic encephalopathy in school-aged children
- FIRES
- Fever-induced refractory epileptic encephalopathy in school-aged children
- Idiopathic catastrophic epileptic encephalopathy
- Severe refractory status epilepticus owing to presumed encephalitis
Inheritance type
Not applicable
Age of Onset
- All ages
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