Humero-radio-ulnar synostosis

What is Humero-radio-ulnar synostosis?

Humero-radio-ulnar synostosis is an extremely rare, genetic, congenital joint formation defect disorder characterized by uni- or bilateral fusion of the humerus, radius and ulnar bones, leading to loss of elbow motion and, in most, functional arm incapacity. It may appear as distal humeral bifurcation with absent elbow joint and shortened arm length on imaging. Hand abnormalities, namely oligoectrosyndactyly, may be associated.

Other condition names

  • Humero-radio-ulnar fusion

Inheritance type



  • Worldwide: <1 in 1,000 000

Age of Onset

  • Antenatal
  • Neonatal
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