What is Leiomyosarcoma?

A rare soft tissue sarcoma characterized by a malignant space-occupying lesion most commonly located in the retroperitoneum or the inferior vena cava, but also other soft tissues, and composed of cells showing distinct features of smooth muscle cells. The tumor presents with mass effect depending on the location. It is capable of both local recurrence and distant metastasis, while lymph node metastasis is rare. Prognosis largely depends on tumor location and size.

Inheritance type

Not applicable


  • Worldwide: Unknown

Age of Onset

  • Adolescent
  • Adult
  • Childhood
  • Elderly
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