What is Myelomeningocele?

A rare neural tube closure defect characterized by protrusion of the spinal cord and meninges from the spinal column into a fluid-filled sac at the location of the defect. Clinical signs are variable, depending on location and severity of the lesion, but may include bladder and bowel dysfunction, hydrocephalus, and/or partial or complete paralysis of the lower limbs, among others.

Inheritance type

Multigenic/multifactorial, Not applicable

Age of Onset

  • Infancy
  • Neonatal
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