Non-amyloid monoclonal immunoglobulin deposition disease

What is Non-amyloid monoclonal immunoglobulin deposition disease?

A rare, secondary glomerular disease characterized by proteinuria, dysproteinemias, nephrotic syndrome, and nodular glomerulopathy leading to renal failure, with or without extra-renal manifestations. The renal biopsy shows typical deposits of monoclonal immunoglobulins that do not show a fibrillar organization and are negative for Congo red staining. Associated signs and symptoms depend on the involvement of other organs, liver, heart, nerve fibers, gastrointestinal tract, or skin.

Other condition names

  • Non-amyloid MIDD
  • Randall disease

Age of Onset

  • Adult
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