OSLAM syndrome

What is OSLAM syndrome?

OSLAM syndrome is characterised by the association of osteosarcoma, limb anomalies (clinodactyly with brachymesophalangy, bilateral radioulnar synostosis and absence of one digital ray of the foot) and red cell macrocytosis without anaemia.

Other condition names

  • Osteosarcoma-limb anomalies-erythroid macrocytosis syndrome

Inheritance type

Autosomal dominant


  • Worldwide: <1 in 1,000 000

Age of Onset

  • Neonatal
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