PFAPA syndrome

What is PFAPA syndrome?

PFAPA (Periodic fever - aphthous stomatitis- pharyngitis - adenopathy) syndrome is an auto inflammatory syndrome characterized by recurrent febrile episodes associated with aphthous stomatitis, pharyngitis and cervical adenitis.

Other condition names

  • Marshall syndrome with periodic fever
  • Periodic fever-aphtous stomatitis-pharyngitis-adenopathy syndrome

Inheritance type



  • Worldwide: Unknown

Age of Onset

  • Childhood
  • Infancy
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "". Data version 1.3.16 / 4.1.7.