Simpson-Golabi-Behmel syndrome

What is Simpson-Golabi-Behmel syndrome?

Simpson-Golabi-Behmel syndrome (SGBS, also referred to as SGBS type 1) is a rare X-linked multiple congenital anomalies syndrome, characterized by pre- and postnatal overgrowth, distinctive craniofacial features, variable congenital malformations, organomegaly and an increased tumor risk.

Other condition names

  • DGSX
  • Golabi-Rosen syndrome
  • SDYS
  • SGBS
  • SGBS1
  • Simpson dysmorphia syndrome
  • Simpson-Golabi-Behmel syndrome type 1
  • X-linked dysplasia gigantism syndrome

Inheritance type

X-linked recessive


  • Worldwide: Unknown

Age of Onset

  • Antenatal
  • Childhood
  • Infancy
  • Neonatal
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