Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease, is the most common subtype of type 1 autosomal dominant cerebellar ataxia (ADCA type 1; see this term), a neurodegenerative disorder, and is characterized by ataxia, external progressive ophthalmoplegia, and other neurological manifestations.
Other condition names
Azorean disease of the nervous system
MJD
Machado disease
Machado-Joseph disease
Nigro-spino-dentatal degeneration with nuclear ophthalmoplegia