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Thrombotic thrombocytopenic purpura

What is Thrombotic thrombocytopenic purpura?

Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA; see this term) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP (see these terms).

Other condition names

  • Moschcowitz disease
  • TTP

Inheritance type

Autosomal recessive, Multigenic/multifactorial

Age of Onset

  • All ages
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.