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Thrombotic thrombocytopenic purpura

What is Thrombotic thrombocytopenic purpura?

An aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of a congenital (cTTP) and acquired, immune-mediated (iTTP) form.

Other condition names

  • Moschcowitz disease
  • TTP

Inheritance type

Autosomal recessive, Multigenic/multifactorial

Age of Onset

  • All ages
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.