Van der Woude syndrome

What is Van der Woude syndrome?

Van der Woude syndrome (VWS) is a rare congenital genetic dysmorphic syndrome characterized by paramedian lower-lip fistulae, cleft lip with or without cleft palate, or isolated cleft palate.

Other condition names

  • Cleft lip/palate with mucous cysts of lower lip
  • Lip-pit syndrome
  • VWS

Inheritance type

Autosomal dominant, Not applicable


  • United States: 1-9 in 1,000 000
  • Europe: 1-9 in 100,000

Age of Onset

  • Neonatal
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