Wolfram syndrome
What is Wolfram syndrome?
A rare, genetic, endocrine disorder characterized by type I diabetes mellitus (DM), diabetes insipidus (DI), sensorineural deafness (D), bilateral optical atrophy (OA) and neurological signs.
Other condition names
- DIDMOAD syndrome
- Diabetes insipidus-diabetes mellitus-optic atrophy-deafness syndrome
- Diabetes insipidus-diabetes mellitus-optic atrophy-hearing loss syndrome
Inheritance type
Autosomal recessive
Prevalence
- Worldwide: 1-9 in 1,000 000
- Europe: 1-9 in 1,000 000
Age of Onset
- Adolescent
- Adult
- Childhood
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.