Young-onset Parkinson disease

What is Young-onset Parkinson disease?

Young-onset Parkinson disease (YOPD) is a form of Parkinson disease (PD), characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most YOPD forms.

Other condition names

  • Early-onset Parkinson disease
  • YOPD

Inheritance type

Autosomal recessive


  • Europe: 1-5 in 10,000

Age of Onset

  • Adult
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