Wild Type ATTR Amyloidosis

What is Wild Type ATTR Amyloidosis?

A rare systemic amyloidosis characterized by combination of various symptoms, depending on the organ involved. Common clinical features are cardiac failure, cardiac conduction anomalies or arrhythmia, renal dysfunction, carpal tunnel syndrome and spinal canal stenosis. Histology reveals fibrillary amyloid deposition of wild type transthyretin mostly in the kidneys, heart, gastrointestinal tract, skin and tenosynovial tissue.

Other condition names

  • ATTRwt amyloidosis
  • ATTRwt-related amyloidosis
  • SSA
  • Senile systemic amyloidosis
  • Wild type ATTR-related amyloidosis

Inheritance type

Not applicable


  • Worldwide: 1-5 in 10,000

Age of Onset

  • Adult
  • Elderly
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.