Erdheim-Chester disease

What is Erdheim-Chester disease?

Erdheim-Chester disease (ECD), a non-Langerhans form of histiocytosis, is a multisystemic disease characterized by various manifestations such as skeletal involvement with bone pain, exophthalmos, diabetes insipidus, renal impairment and central nervous system (CNS) and/or cardiovascular involvement.

Inheritance type

Not applicable


  • Worldwide: Unknown

Age of Onset

  • Adult
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