Pseudohypoparathyroidism type 1C

What is Pseudohypoparathyroidism type 1C?

Pseudohypoparathyroidism type 1c (PHP1c) is a rare type of pseudohypoparathyroidism (PHP; see this term) characterized by resistance to parathyroid hormone (PTH) and other hormones, which manifests with hypocalcemia, hyperphosphatemia and elevated PTH levels, a constellation of clinical features collectively termed Albright's hereditary osteodystrophy (AHO; see this term), but normal activity of the stimulatory protein G (Gs alpha).

Inheritance type

Autosomal dominant


  • Europe: Unknown

Age of Onset

  • Childhood
  • Infancy
  • Neonatal
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