CLAPO syndrome

What is CLAPO syndrome?

CLAPO syndrome is a newly described syndrome consisting of capillary malformation of the lower lip (C), lymphatic malformation of the face and neck (L), asymmetry of face and limbs (A) and partial or generalized overgrowth (O).

Inheritance type



  • Worldwide: <1 in 1,000 000

Age of Onset

  • Infancy
  • Neonatal
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