Recessive X-linked ichthyosis

What is Recessive X-linked ichthyosis?

Recessive X-linked ichthyosis (RXLI) is a genodermatosis belonging to the Mendelian Disorders of Cornification (MeDOC) and characterized by generalized hyperkeratosis and scaling of the skin.

Other condition names

  • RXLI
  • Steroid sulfatase deficiency
  • X-linked ichthyosis
  • XLI

Inheritance type

X-linked recessive


  • Europe: 1-5 in 10,000

Age of Onset

  • Neonatal
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "". Data version 1.3.16 / 4.1.7.