HANAC syndrome

What is HANAC syndrome?

A rare multisystemic disease characterized by small-vessel brain disease, cerebral aneurysm, and extracerebral findings involving the kidney, muscle, and small vessels of the eye.

Other condition names

  • Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome
  • Hereditary angiopathy-nephropathy-aneurysms-muscle cramps syndrome

Inheritance type

Autosomal dominant


  • Worldwide: <1 in 1,000 000

Age of Onset

  • Childhood
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.