Spontaneous periodic hypothermia

What is Spontaneous periodic hypothermia?

A rare neurologic disorder characterized by spontaneous periodic hypothermia and hyperhidrosis in the absence of hypothalamic lesions.

Other condition names

  • Episodic spontaneous hypothermia
  • Shapiro syndrome

Inheritance type



  • Worldwide: <1 in 1,000 000

Age of Onset

  • All ages
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on "https://www.orphadata.com". Data version 1.3.16 / 4.1.7.